Nauki Medyczne

Folia Medica Cracoviensia

Zawartość

Folia Medica Cracoviensia | 2022 | Vol. 62 | No 2

Abstrakt

Purpose: Oral health and diseases are significant components of general health. However, oral health-care remains at the lowest of older patients’ priorities. The inability to obtain dental care can result in progression of dental disease, leading to a diminished quality of life and overall health. Teledentistry (TD) provides an opportunity to improve the quality of oral health services. The aim of our narrative review was to analyze the usefulness of teledentistry as a part of telemedicine to improve oral health in the elderly.
Materials/Methods: The PubMed database search was done for: teledentistry, oral health, oral- health related diseases, elderly, older adults.
Results: The applicability of TD has been demonstrated from children to older adults. Older adults have many obstacles in getting oral health care, including low income, lack health insurance, frailty, anxiety, depression, mobility problems or other handicaps. Available data suggests that the usefulness of TD in the provision of oral care in elderly people living in residential aged care facilities. Moreover, TD procedures were found to be as accurate as traditional face-to-face dental examinations, they was cost-effective and well accepted among patients and caregivers.
Conclusions: TD might be a very useful tool for professional education, improving access and patient satisfaction of dental care. However, such TD modes would be difficult to widely implementation in community-dwelling older people who cannot access dental care. The ongoing “Patient centric solution for smart and sustainable healthcare (ACESO)” project will add to the intelligent oral health solutions.
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Autorzy i Afiliacje

Barbara Gryglewska
1 2
Ian Perera
2
Ewa Klimek
1 2
Małgorzata Fedyk-Łukasik
1 2
Karolina Piotrowicz
1 2
Irina Mocanu
3
Ligia Muntianu
4
Jerzy Gąsowski
1 2

  1. Department of Internal Medicine and Gerontology, Jagiellonian University Medical College, Kraków, Poland
  2. University Hospital, Kraków, Poland
  3. Centrul IT Pentru Stiinta si Tehnologie, and Computer Science Department, University Politehnica of Bucharest, Romania
  4. UMF Carol Davila Bucharest Faculty of Dental Medicine, Department of Removable Prosthodontics, Bucharest, Romania

Abstrakt

The dorsal capsule of the wrist and the DCSS may play a significant role in the conduction of nerve signals transmitted from proprioceptors present in SL to PIN, which is located above the dorsal capsule. Hence, this study aimed to determine if nerve fibers of PIN penetrate inside the dorsal capsule. The dorsal capsules of the wrist were dissected from both sides from 15 cadavers. Eventually, 30 dorsal capsules were dissected. It can be concluded that the PIN nerve fibers penetrate the dorsal capsule of the wrist, as the penetration was noticeable in every part evaluated.
The present study proves that afferent fibers from the mechanoreceptors of the SLIL potentially pass through the DCSS and subsequently through the dorsal capsule of the wrist to the PIN. This knowledge can surely be of great use for hand surgeons that perform procedures on the dorsal wrist.
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Autorzy i Afiliacje

Michał Bonczar
1
Tomasz Bonczar
1
Patryk Ostrowski
1
Martyna Dziedzic
1
Mariusz Bonczar
1
Dawid Plutecki
2
Anna Gil
1
Małgorzata Jasińska
3
Grzegorz Lis
3
Jerzy Walocha
1
Mateusz Koziej
1

  1. Department of Anatomy, Jagiellonian University Medical College, Kraków, Poland
  2. Collegium Medicum, Jan Kochanowski University, Kielce, Poland
  3. Department of Histology, Jagiellonian University Medical College, Kraków, Poland

Abstrakt

5-fluorouracil (5-FU), which is a commonly used chemotherapy agent exerts undesired cardiac toxicity. Mitochondrial dysfunction is thought to be one of potentially important mechanisms of 5-FU- induced cardiotoxicity. α-ketoglutarate dehydrogenase (α-KGDHC) is the key regulatory enzyme of TCA cycle. The complex consists of multiple copies of three catalytic subunits: α-ketoglutarate dehydrogenase (E1), dihydrolipoamide succinyltransferase (E2) and dihydrolipoamide dehydrogenase (E3). α-KGDHC together with branched chain α-ketoacid dehydrogenase (BCKDHC) and pyruvate dehydrogenase (PDHC), are the members of 2-oxoacid dehydrogenases family that share some structural and functional similarities. Recently, it has been found that 5-FU stimulates BCKDHC in rat’s cardiac muscle. Therefore, we hypothesize that 5-FU modifies α-KGDHC activity and affects cardiac muscle metabolism. The aim of this study was to determine the effect of 5-FU on α-KGDHC activity and protein levels of E1 and E2 subunits of the complex in rat’s cardiac muscle. Wistar male rats were administered with 4 doses of 5-FU, 150 mg/kg b.wt. each (study group) or 0.3% methylcellulose (control group). α-KGDHC activity was assayed spectrophotometrically. The E1 and E2 proteins levels were quantified by Western blot. 5-FU administration resulted in stimulation of myocardial α-KGDHC activity in rats. In addition, E2 protein level increased in response to 5-FU treatment, while the E1 protein level remained unchanged. Up- regulation of α-KGDHC appears to result from change in E2 subunit protein level. However, the effect of 5-FU on factors modifying α-KGDHC activity at post-translational level cannot be excluded.
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Autorzy i Afiliacje

Małgorzata Knapik-Czajka
1
Anna Gawędzka
1
Michał Jurczyk
2
Jagoda Drąg
1
Małgorzata Belczyk
1
Veronika Aleksandrovych
2
Anna Gil
3
Krzysztof Gil
1

  1. Department of Biochemical Analytics, Jagiellonian University Medical College, Kraków, Poland
  2. Department of Pathophysiology, Jagiellonian University Medical College, Kraków, Poland
  3. Department of Anatomy, Jagiellonian University Medical College, Kraków, Poland

Abstrakt

Objectives: The aim of the study was to assess the relationship between body composition, nutritional status and physical ability in elderly outpatients.
Method:. In this cross-sectional study, demographic data and medical history were collected from patients aged ≥60 years followed in the Geriatric Outpatient Clinic from October 2010 to February 2014. Body composition was examined using a dual-energy X-ray absorptiometry. Physical performance was assessed by gait speed (GS), Timed Up & Go Test (TUG), Six Minute Walk Test (6MWT). The nutritional status was evaluated using the Mini Nutritional Assessment (MNA) and serum albumin level.
Results: Mean age (± SD) of 76 patients (64.47% men) was 71.93 ± 8.88 yrs. The most common diseases were: hypertension (89.47%), coronary heart disease (81.58%) and chronic heart failure (68.4%). In multiple regression analyses, the factors significantly affecting GS were: age (B = –0.017, p ≤0.0001), good nutritional status (B = 0.038, p <0.01) and percent of lower extremity fat (B = –0.009, p <0.05). Longer TUG time was associated with poorer nutritional status (B = –0.031, p <0.01), older age (B = 0.01, p <0.01) and a higher number of comorbidities (B = 0.034, p <0.05). 6MWT was influenced negatively by age (B = –3.805, p <0.01) and percent of lower extremity fat (B = –2.474, p <0.05).
Conclusions: Age and nutritional status remain a strong determinant of physical fitness deterioration. Different measures of physical performance are influenced by different elements of body composition — no single element of body composition was found determining the deterioration of all assessed parameters of physical fitness.
Identifying the relationship between body composition, nutritional status and physical performance can help elucidate the causes of disability and target preventive measures.
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Autorzy i Afiliacje

Paulina Fatyga-Kotula
1
Barbara Wizner
2
Małgorzata Fedyk-Łukasik
2
Tomasz Grodzicki
2
Anna Skalska
2

  1. Department of Toxicology and Occupational Diseases, Jagiellonian University Medical College, Kraków, Poland
  2. Department of Internal Medicine and Gerontology, Jagiellonian University Medical College, Kraków, Poland

Abstrakt

There is a discrepancy between the research exploring e-learning at medical universities in Central/Eastern and Western European countries. The aim of the MeSPeLA study was to explore the understanding, experience and expectations of Polish medical students in terms of e-learning. Questionnaire containing open-ended and closed questions supplemented by focus group discussion was validated and performed among 204 medical students in Poland before COVID-19 pandemia. Several domains: understanding of e-learning definitions; students’ experience, preferences, expectations and perceptions of e-learning usefulness, advantages and disadvantages were addressed. The qualitative data were analyzed using an inductive approach. 46.0% of students chose a communication-oriented definition as the most appropriate. 7.4% claimed not to have any experience with e-learning. 76.8% of respondents indicated they had contact with e-learning. The main reported e-learning advantages were time saving and easier time management. The most common drawback was limited social interactions. The acceptance of the usage of e-learning was high. Medical undergraduates in Poland regardless of the year of studies, gender or choice of future specialization showed positive attitudes towards e-learning. Students with advanced IT skills showed a better understanding of the e-learning definition and perceived e-learning to be a more useful approach. The expectations and perceptions about e-learning in Polish medical schools seems similar to some extent to that in Western European and the United States so we can be more confident about applying some lessons from these research to Poland or other post-communist countries. Such application has been accelerated due to COVID-19 pandemia.
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Autorzy i Afiliacje

Mirosława Püsküllüoğlu
1
Michał Nowakowski
2
Sebastian Ochenduszko
3
David Hope
4
Helen Cameron
5

  1. Department of Clinical Oncology, Maria Sklodowska-Curie National Research Institute of Oncology, Cracow Branch, Kraków, Poland
  2. 2nd Department of General Surgery, Jagiellonian University Medical College, Kraków, Poland
  3. Department of Medical Oncology, Hospital Universitario Dr Peset, Valencia, Spain
  4. Centre for Medical Education, The Chancellor’s Building, College of Medicine and Veterinary Medicine, The University of Edinburgh, Edinburgh, Scotland
  5. Aston Medical School, Aston University, Birmingham, UK

Abstrakt

Introduction: The COVID-19 pandemic has put healthcare systems worldwide under huge strain, resulting in a significant loss of their capacity and availability. Patients have become more reluctant to contact their doctors or call an ambulance in case of myocardial infarction (MI) symptoms onset. It has been accompanied by a significant decrease in the number of coronary angiography and PCI procedures performed.
Objectives: The aim of the study is to evaluate the role of online health information in the patient- dependent phase of MI management during the COVID-19 lockdown in Europe.
Methods: We analyzed Google Trends data on the popularity of phrases related to MI symptoms, respiratory tract infection, urological complaints, and terms unrelated to health, for the period of the first COVID-19 lockdown, along with the data from the corresponding weeks from 2017–2019 in seven European countries.
Results: The search volume for particular symptoms of myocardial infarction increased in all studied countries, compared to the analogous period from 2017–2019, with a significant increase in for chest pain, shortness of breath, fear, and palpitations in most countries. These changes have not been accompanied by increased interest in terms related to respiratory tract infection symptoms and urological complaints.
Conclusions: Our findings suggest that during lockdown, patients with MI symptoms may have tried to manage their complaints on their own, using information from the Internet. This demonstrates the growing role of the Internet in the patient’s decision-making process in the emergency situation, indicating a grow-ing need for reliable and freely available online information provided by healthcare professionals.
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Autorzy i Afiliacje

Dominik Felkle
1
Michał Ł. Korman
1
Andrzej Surdacki
2

  1. Students’ Scientific Group at Second Department of Cardiology, Institute of Cardiology, Faculty of Medicine, Jagiellonian University Medical College, Kraków, Poland
  2. Second Department of Cardiology, Institute of Cardiology, Faculty of Medicine, Jagiellonian University Medical College, Kraków, Poland

Abstrakt

Tenosynovial Giant Cell Tumor (TGCT) is a group of typically benign lesions arising from the synovium of joints, bursae and tendon sheaths. Depending on their growth pattern and clinical course, they are divided into localized and diffuse types. It is predominantly caused by a mutation in the stromal cells of the synovial membrane leading to overexpression of the colony stimulating factor 1 that recruits CSF1R-expressing cells of the mononuclear phagocyte lineage into the tumor mass. The lesions contain mainly histiocyte-like and synovial cells accompanied by varying numbers of multinucleated giant cells, mononuclear cells, foam cells, inflammatory cells and hemosiderin deposits. The gold standard for detect-ing and monitoring the disease is MRI, where the characteristic hemosiderin accumulation can be best appreciated, but it is a histological examination that is most conclusive. The main treatment is surgical resection of all pathological tissue, but radio- and chemotherapy are also viable options for certain groups of patients.
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Autorzy i Afiliacje

Monika Kager
1
Richard Kager
2
Paulina Fałek
3
Artur Fałek
3
Grzegorz Szczypiór
4
Joanna Niemunis-Sawicka
4 5
Ludomira Rzepecka-Wejs
6
Elżbieta Starosławska
1
Franciszek Burdan
1 7

  1. Radiology Department, St Johns’ Cancer Center, Lublin, Poland
  2. Public Independent Clinical Hospital Number 4, Lublin, Poland
  3. Independent Public Healthcare, Puławy, Poland
  4. MRI Unit of Maritime Medical Center, Gdańsk, Poland
  5. 2nd Radiology Department, Medical University of Gdańsk, Gdańsk, Poland
  6. Goris-Med, Gdańsk, Poland
  7. Human Anatomy Department, Medical University of Lublin, Lublin, Poland

Abstrakt

Arterial stiffness is a characteristic of the arterial wall strongly associated with ageing and hypertension. It has been confirmed as a significant cardio-vascular risk factor. Despite available non- invasive measurement methods of central artery stiffening, it has not become a prevalent diagnostic marker in primary care so far. This article provides an overview of pathophysiology of arterial stiffness, possible diagnostic techniques, association with cardiovascular conditions and potential perspective of primary care to implement an additional distinctive parameter to evaluate cardiac risk.
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Autorzy i Afiliacje

Anna Kamieńska
1
Sławomir Chlabicz
1

  1. Department of Family Medicine, Medical University of Białystok, Poland

Abstrakt

Pain in the masticatory muscles or temporomandibular joints may in some cases be a symptom of other afflictions occurring in this region. The aim of the study was to present the differential diagnosis of temporomandibular disorders (TMD) and other diseases in the craniofacial area, based on review of the literature. Using the key words: “differential diagnosis of TMD”, “pain of non-dental origin” and “chronic orofacial pain”, PUBMED and Scopus databases were systematically searched for articles in English from 2005 to 2020. Additionally, the PUBMED database was supplementarily reviewed using the keywords “Lyme disease orofacial symptoms” for the English-language articles published in the years 1996–2020. Out of 445 publications from PUBMED and Scopus databases as well as other sources, 57 articles describ-ing the pathogenesis and characteristic symptoms of diseases that may cause pain similar to that occurring in TMD as well as diagnostic methods used in differential diagnosis of TMD were selected for analysis. Dental and jawbones-related conditions, ear and maxillary sinus diseases, as well as ailments of neuro-pathic and vascular origin, were taken into account. Neoplastic processes taking place in this region and less often occurring diseases caused by viruses, bacteria and parasites were also described. Conclusions. Correct diagnosis of temporomandibular disorders is based on medical history and thorough physical examination, as well as results of additional tests. Pain localized in the head and neck structures may have diverse, sometimes complex aetiology, and may require multidisciplinary treatment. Observation of the patient’s behaviour and — in selected cases — the results of additional laboratory tests, also play a sig-nificant role.
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Autorzy i Afiliacje

Magdalena Krasińska-Mazur
1
Paulina Homel
1
Andrzej Gala
1
Justyna Stradomska
1
Małgorzata Pihut
1

  1. Department of Prosthodontics and Orthodontics, Institute of Dentistry, Jagiellonian University Medical College, Kraków, Poland

Abstrakt

Chronic pain in the head and face region has a predicted prevalence of 20% in Europe, and is more common in women than men. The etiology of temporomandibular disorder (TMD) is multifactorial, and high levels of psychological stress amplify its symptoms. We were interested in how headache reported in RDC/TMD is associated with stress. Individuals with an average age of 18 years were included in the study. They were all volunteer participants in a research project. Clinical evaluation of each subject was performed using the RDC/TMD dual-axis diagnostic system. All participants filled out the PSS-10 ques-tionnaire. A total of 138 individuals participated in the study, of which 107 were female. Headache was reported by 83 participants (59.4%), with females presenting higher scores on the PSS-10; this was statistically significant. A comparison between PSS-10 questionnaire results and headache level shows insignificant differences. However, the higher the stress level in the participant, the higher the headache score. Females are more susceptible to perceived stress, which can have an effect on TMD.
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Autorzy i Afiliacje

Aneta Wieczorek
1
Małgorzata Pihut
1
Jolanta E. Loster
1

  1. Department of Prosthodontics and Orthodontics, Institute of Dentistry, Faculty of Medicine, Jagiellonian University Medical College, Kraków, Poland

Instrukcja dla autorów

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