The objective of this study was to evaluate the effects of dietary zeolite clinoptilolite on re- productive performance, serum progesterone and insulin-like growth factor 1 (IGF-1) concentra- tions in 78 Holstein Friesian (HF) cows during pregnancy and lactation. The cows were divided into two groups comprising 40 (control group; CON) and 38 (CPL group) cows. To assess repro- ductive performance of HF cows the following variables were registered: the interval from calv- ing to first insemination (days open to first service, DFS), the interval from calving to pregnancy (days open to pregnancy, DOP), and the number of services per pregnancy (NSP). The average values of progesterone (5.64±0.59 ng/mL vs. 5.16±0.64 ng/mL) were not statistically different (p<0.05) and IGF-1 levels (400.17±17.72 ng/mL vs. 348.36±20.39 ng/mL) were higher in the CON than in the CPL group which received 50 g of clinoptilolite twice a day. However, in the CPL group ovarian cyclity resumed on days 40 and 60 postpartum. In addition, DFS (p<0.05) and DOP (p>0.05) were shorter in the CPL than in the CON group (115.1±19.9 and 137.5±36.3 days vs. 124.2±17.3 and 143.8±33.5 days, respectively). During 305 days of lactation, milk production was higher in the CPL vs. CON (8325.5±628.8 kg vs. 8050±586.8 kg). The NSP was lower in the CPL than in CON group (1.91 vs. 2.14). The dietary clinoptilolite supplement had a positive in- fluence on milk yield, exhibited modulating effects on endocrine status of dairy cows, and im- proved reproductive performance, with the decreased NSP, and fewer DFS and DOP.

The aim of the study was to examine identity statuses in various life domains and the relationship between identity and well-being. We adopted the three-dimensional model of identity (Crocetti et al., 2008), including: in-depth exploration, commitment, and reconsideration of commitment. Moreover, in accordance with domain-specific approach (Goossens, 2001), we sought to empirically derive identity statuses in various life domains. The participants included 835 emerging adults (Mage = 21.81, SD = 2.33). We examined eight domains previously identified in qualitative research: personality characteristics, past experiences, family, friends and acquaintances, worldview, hobbies and interests, aims and plans for the future, and occupation. To measure three identity processes, we used a modified version of the Utrecht-Management of Identity Commitments Scale (Crocetti et al., 2008) and to measure well-being we used the Mental Health Continuum-Short Form (Keyes, 2013). Results indicate that, although the statuses identified in previous research were, to a large extent, replicated (except moratorium), people were classified in different statuses in different domains; thus, we conclude that talking about statuses should be limited to a given domain. Well-being was the highest in achievement statuses and the lowest in diffusion, but only in two examined domains: personality characteristics and past experience.

Canine status epilepticus (CSE) is characterized by epileptic seizures that are longer than 5 min or more than one seizure with incomplete recovery. Currently, diazepam suppositories are generally prescribed for CSE. Levetiracetam (LEV) is one of the newest antiepileptic drugs currently available. This study compared the pharmacokinetics of intragastric and intrarectal administration in oral formula of LEV in four healthy beagles as a reference data when the owner administers levetiracetam to dogs by himself at home. Blood for measuring plasma LEV concen- trations was collected 0, 30, 60, 90, 120, 240, 360, and 540 min after LEV administration. The time to reach the maximum plasma concentration (Tmax) was markedly shorter with intra- rectal administration (45±26 min) than with intragastric administration (270±99 min). Intrarectal administration of LEV tablets could be an effective option for treating canine seizures although it might be a limit for treating CSE because the absorption rate is not fast enough.

The use of lactoferrin (LF) and/or lactobacillus sp. (LB) to improve animal health and production has increased recently. However, information regarding the immune-modulatory role of LB supplementations either alone or in combination with LF in sheep remains unclear. Therefore, the present study was designed to evaluate the immune modulating properties and the antioxidant activity of supplementing commercially available LF and/or LB in healthy lambs. For this reason, twenty-four apparently healthy Ossimi lambs were used. After three weeks of acclimatization, the lambs were randomly allocated to four equal-sized groups and assigned to receive one of the following supplements: LB at a dose of ~ 1 g active ingredient/head (group 1), LF at a dose rate of 0.5 gm /head (group 2), a combination of both treatments using the same dosing regimens (group 3), and (group 4) received only 10 mL of isotonic saline and was considered as a control group. All supplements were given orally twice daily for 30 consecutive days. Blood samples were collected from each lamb before starting the experiment (T0) and two weeks (T15), and four weeks (T30) after giving supplements for hematological examinations, serum biochemical analyses, and RT-PCR assays. Our findings demonstrated that lambs receiving LB showed statistically significant (P<0.05) higher values of total leucocytes, lymphocytes and lysozyme activity than those receiving LF. In contrast, lambs that received LF had significantly (P< 0.05) higher values of serum catalase, nitric oxide and GSH with a significantly lower MDA level compared with those supplemented with LB. A combination of LF and LB supplementation elicited maximal up-regulation of Tollip, TLR4, IL-5, and IL-6 gene expression compared with other groups. The results suggest that bovine LF and or LB could be used as useful nutritional supplements to support the immune system in healthy lambs.

The article’s aim is to show that La Fronde, a daily founded by Marguerite Durand, is a place of various manifestations, especially the will to change the political and social domain, and above all the status of a woman in society. The analytical corpus includes texts dealing with political rights (voting rights) and civil rights (the right to work), which were published in January and February 1899.

Artykuł składa się z części krytycznej oraz pozytywnej. Część krytyczna stanowi polemikę z dwoma najbardziej rozpowszechnionymi uzasadnieniami na rzecz utożsamienia całkowitej niewydolności mózgu (tzw. śmierci mózgowej) ze śmiercią człowieka. Zgodnie z jednym z nich, śmierć ma miejsce wtedy, gdy dochodzi do somatycznej dezintegracji organizmu. Natomiast drugie uzasadnienie, zaproponowane w 2008 r. przez President’s Council on Bioethics, utożsamia śmierć z utratą zdolności do samozachowania. W części zawierającej pozytywną argumentację autor przedstawia alternatywną koncepcję, według której śmierć, w znaczeniu, jakie jest istotne z perspektywy praktyki medycznej, jest tożsama z nieodwracalną utratą cech stanowiących o tym, że dana istota posiada status moralny. Nowa koncepcja pozwala utożsamić stan całkowitej niewydolności mózgu ze śmiercią człowieka oraz daje podstawę do opracowania bardziej precyzyjnych medycznych kryteriów śmierci.

The aim of this analysis of the oneiric representations of phantom women in the poetry of Kazimierz Przerwa-Tetmajer and Bolesław Leśmian is to compare and characterize the workings of the poetic imagination of a pair of poets who represent the first and the second generation of the Young Poland movement. Their poems are read and interpreted within the framework of Young Poland's conceptualization of dreams and its use of the dream motif so as to explain the functioning and the ontological status of the oneiric female characters. The analysis shows that both Przerwa-Tetmajer's and Leśmian's apparitions belong to more than one category. While some are wholly imaginary, others are known to have existed as real persons and have merely been transposed into an image of a man's mind.