TY - JOUR N2 - Studies in human medicine have shown that in addition to affecting the reproductive system, the hormone estrogen also has cardioprotective effects. The present study hypothesized that ovariohysterectomized (OVH) dogs would have a higher incidence of cardiac dysfunction and impairment of lipid profiles compared to intact female dogs. Thirty healthy female dogs were divided into two groups, 15 intact female dogs and 15 OVH dogs. All the dogs underwent a physical examination, including investigation of physical parameters, blood collection for lipid profile measurement, thoracic radiography, electrocardiography and echocardiography. Physical examination parameters, electrocardiographic parameters, heart size and cardiac function in OVH dogs were not different when compared to intact female dogs. However, in the OVH dogs, triglyceride and very-low-density lipoprotein levels were increased, while high-density lipoprotein was significantly decreased compared to the intact female dogs (P<0.05). Differences between the groups in total cholesterol and low-density lipoprotein did not reach statistical signi- ficance. We concluded that estrogen deprivation in dogs can induce lipid profile impairment but not cardiac performance impairment 1 year after an ovariohysterectomy. L1 - http://www.czasopisma.pan.pl/Content/117733/PDF/6.pdf L2 - http://www.czasopisma.pan.pl/Content/117733 PY - 2020 IS - No 4 EP - 528 DO - 10.24425/pjvs.2020.134701 KW - dog KW - estragon KW - ovariohysterectomy KW - cardiac function KW - lipid profiles A1 - Boonyapakorn, C. A1 - Punyapornwithaya, V. A1 - Sawatphakdee, G. A1 - Poolsawat, N. A1 - Pongkan, W. PB - Polish Academy of Sciences Committee of Veterinary Sciences PB - University of Warmia and Mazury in Olsztyn VL - vol. 23 DA - 2020.12.28 T1 - Estrogen deprivation induces lipid profile impairment but not cardiac dysfunction in ovariohysterectomized dogs SP - 521 UR - http://www.czasopisma.pan.pl/dlibra/publication/edition/117733 T2 - Polish Journal of Veterinary Sciences ER -