@ARTICLE{Rakoczy_Rafał_Two-stage_2022, author={Rakoczy, Rafał and Konopacki, Maciej and Kordas, Marian and Grygorcewicz, Bartłomiej}, volume={vol. 43}, number={No 4 (3rd Seminar on Practical Aspects of Chemical Engineering PAIC 2022, 7–8 June 2022, Zaniemyśl, Poland. Guest editor: Prof. Marek Ochowiak)}, journal={Chemical and Process Engineering}, pages={491-506}, howpublished={online}, year={2022}, publisher={Polish Academy of Sciences Committee of Chemical and Process Engineering}, abstract={The practical applications of bacteriophages are associated with the problems related to the intensification, optimization of process production of this biomaterial and the search for new methods of production. The production of bacteriophages requires a fine balance between the dynamic growth of the bacteriophage and the host. The electromagnetic field (EMF) is a promising biotechnological method for the process production of bacteriophages. This study evaluates the use of various types of EMF to enhance the process. It was found that the process production of bacteriophages is divided into two stages. In the first stage, the influence of various types of EMF on the proliferation process of bacteria (host) was analyzed. Secondly, the process production of bacteriophage was implemented for the optimal infection conditions under the action of the various types of EMF. Moreover, the study demonstrated that the most effective bacteriophage production was the process with the application of the rotating magnetic field (RMF), pulsed magnetic field (PMF) and the static magnetic field (SMF) with negative polarity.}, type={Article}, title={Two-stage bacteriophage production process supported by the electromagnetic field}, URL={http://www.czasopisma.pan.pl/Content/125946/PDF/art06_int.pdf}, doi={10.24425/cpe.2022.142289}, keywords={bioreactor, biotechnology, bacteriophage production, electromagnetic field}, }