@ARTICLE{Kosowska_Katarzyna_The_2017, author={Kosowska, Katarzyna and Henczka, Marek}, volume={vol. 38}, number={No 4}, journal={Chemical and Process Engineering}, pages={535-541}, howpublished={online}, year={2017}, publisher={Polish Academy of Sciences Committee of Chemical and Process Engineering}, abstract={The results of experimental investigations into foaming process of poly(ε-caprolactone) using supercritical CO2 are presented. The objective of the study was to explore the aspects of fabrication of biodegradable and biocompatible scaffolds that can be applied as a temporary three-dimensional extracellular matrix analog for cells to grow into a new tissue. The influence of foaming process parameters, which have been proven previously to affect significantly scaffold bioactivity, such as pressure (8-18 MPa), temperature (323-373 K) and time of saturation (1-6 h) on microstructure and mechanical properties of produced polymer porous structures is presented. The morphology and mechanical properties of considered materials were analyzed using a scanning electron microscope (SEM), x-ray microtomography (μ-CT) and a static compression test. A precise control over porosity and morphology of obtained polymer porous structures by adjusting the foaming process parameters has been proved. The obtained poly(ε-caprolactone) solid foams prepared using scCO2 have demonstrated sufficient mechanical strength to be applied as scaffolds in tissue engineering.}, type={Artykuły / Articles}, title={The influence of supercritical foaming conditions on properties of polymer scaffolds for tissue engineering}, URL={http://www.czasopisma.pan.pl/Content/105897/PDF/04-paper-Kosowska%20Henczka.pdf}, doi={10.1515/cpe-2017-0042}, keywords={supercritical fluids, supercritical foaming, poly(ε-caprolactone), tissue engineering, scaffold}, }