Biological efficacy of herbicides: propoxycarbazone-sodium (Attribut 70 WG) and sulfosulfuron (Apyros 75 WG) applied with adjuvants was estimated in the field, greenhouse and laboratory experiments. An addition of adjuvants to herbicides Attribut 70 WG and Apyros 75 WG had a positive influence on physical characteristics of tank mixture, herbicidal effect, and the increase of winter wheat grain yield. Ammonium nitrate used as an adjuvant showed the weakest effect. The lowest grain yield was obtained after using the preparations Attribut 70 WG and Apyros 75 WG without adjuvant. Th eoil adjuvants, Adbios 85 SL, A ero 030 SL, Atpolan 80 EC and Olbras 88 EC influenced in a similar manner the activity of tested herbicides. Obtained herbicidal effect, the amount of yield and elements of yield structure were differentiated after joint application of herbicides with adjuvants. The herbicides protected plantations of winter wheat against couch grass (Agropyron repens) during the whole vegetative season. However the herbicide Attribut 70 WG was more effective in controlling regrowth of couch grass after harvest, as compared to Apyros 75 WG. On the other hand, Apyros 75 WG controlled somewhat better broadleaf weeds. Also differences in carryover effect occurred. On the sites after propoxycarbazone–sodium application winter oilseed rape, spring oilseed rape and sugar beet should not be cultivated. On the sites after cereals that were protected against weeds with sulfosulfuron only cultivation of winter oilseed rape should not be recommended, however spring oilseed rape and sugar beet can be grown