For brain tumour treatment plans, the diagnoses and predictions made by medical doctors and radiologists are dependent on medical imaging. Obtaining clinically meaningful information from various imaging modalities such as computerized tomography (CT), positron emission tomography (PET) and magnetic resonance (MR) scans are the core methods in software and advanced screening utilized by radiologists. In this paper, a universal and complex framework for two parts of the dose control process – tumours detection and tumours area segmentation from medical images is introduced. The framework formed the implementation of methods to detect glioma tumour from CT and PET scans. Two deep learning pre-trained models: VGG19 and VGG19-BN were investigated and utilized to fuse CT and PET examinations results. Mask R-CNN (region-based convolutional neural network) was used for tumour detection – output of the model is bounding box coordinates for each object in the image – tumour. U-Net was used to perform semantic segmentation – segment malignant cells and tumour area. Transfer learning technique was used to increase the accuracy of models while having a limited collection of the dataset. Data augmentation methods were applied to generate and increase the number of training samples. The implemented framework can be utilized for other use-cases that combine object detection and area segmentation from grayscale and RGB images, especially to shape computer-aided diagnosis (CADx) and computer-aided detection (CADe) systems in the healthcare industry to facilitate and assist doctors and medical care providers.

The liver is a vital organ of the human body and hepatic cancer is one of the major causes of cancer deaths. Early and rapid diagnosis can reduce the mortality rate. It can be achieved through computerized cancer diagnosis and surgery planning systems. Segmentation plays a major role in these systems. This work evaluated the efficacy of the SegNet model in liver and particle swarm optimization-based clustering technique in liver lesion segmentation. Over 2400 CT images were used for training the deep learning network and ten CT datasets for validating the algorithm. The segmentation results were satisfactory. The values for Dice Coefficient and volumetric overlap error achieved were 0.940 ± 0.022 and 0.112 ± 0.038, respectively for liver and the results for lesion delineation were 0.4629 ± 0.287 and 0.6986 ± 0.203, respectively. The proposed method is effective for liver segmentation. However, lesion segmentation needs to be further improved for better accuracy.

The paper is focused on automatic segmentation task of bone structures out of CT data series of pelvic region. The authors trained and compared four different models of deep neural networks (FCN, PSPNet, U-net and Segnet) to perform the segmentation task of three following classes: background, patient outline and bones. The mean and class-wise Intersection over Union (IoU), Dice coefficient and pixel accuracy measures were evaluated for each network outcome. In the initial phase all of the networks were trained for 10 epochs. The most exact segmentation results were obtained with the use of U-net model, with mean IoU value equal to 93.2%. The results where further outperformed with the U-net model modification with ResNet50 model used as the encoder, trained by 30 epochs, which obtained following result: mIoU measure – 96.92%, “bone” class IoU – 92.87%, mDice coefficient – 98.41%, mDice coefficient for “bone” – 96.31%, mAccuracy – 99.85% and Accuracy for “bone” class – 99.92%.