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Abstract

Alginate – chitosan – alginate multilayer hydrogel encapsulation systems were investigated for

encapsulation of chondrocytes. Hydrogel is crosslinked due to ionic interaction between cationic

chitosan and anionic alginate, and additionally by calcium ions. Two types of chitosan with

molecular weight were investigated. Cells were encapsulated in two shape microcapsules, microbeads with diameter size 300 – 400 and 500 - 600 µm and fibres with diameter 500 - 600 µm. The

work provides a detailed examination of the impact of the microencapsulation process on the growth

of cells. The viability of chondrocytes can be influenced by the size of produced microcapsules,

while the shape of microcapsules has no important significance on cell viability. The applied

encapsulation methods do not contain harmful stages and create conducive conditions for cell

growth. A possible application area of the developed system is dressing and regeneration of

damaged joint cartilage.

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Authors and Affiliations

Iga Wasiak
Tomasz Ciach
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Abstract

An analysis of the effect of feed foaming on the efficiency of sunflower oil encapsulation on selected product properties is presented in the paper. Experiments were carried out in a pilot-plant concurrent spray dryer using the gas-admixing technique. The analysis of the product properties showed that the application of foaming makes it possible to control final product properties, e.g. apparent density, bulk density, distribution of particle diameters, etc. at a high efficiency of sunflower oil encapsulation.

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Authors and Affiliations

Artur Lewandowski
Marcin Czyżewski
Ireneusz Zbiciński

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