Th e forearm is a body region of numerous anatomical variations. Due to its favorable anatomy fl exor digitorum superfi cialis muscle (FDS) is commonly used in tendon transfer surgeries. In this study a unique combination of abnormalities was found in a single forearm: the fl exor digitorum superfi cialis muscle penetrated by the median nerve, one of the fl exor digitorum superfi cialis tendons early division and absence of the palmaris longus muscle. Described variation potentially may lead to the clinical manifestation of the median nerve compression and should be also considered during FDS surgery.