For successful active control with a vibrating plate it is essential to appropriately place actuators. One of the most important criteria is to make the system controllable, so any control objectives can be achieved. In this paper the controllability-oriented placement of actuators is undertaken. First, a theoretical model of a fully clamped rectangular plate is obtained. Optimization criterion based on maximization of controllability of the system is developed. The memetic algorithm is used to find the optimal solution. Obtained results are compared with those obtained by the evolutionary algorithm. The configuration is also validated experimentally.