This paper is the first to optimize the friction stir welding (FSW) process considering the Clamp Pitch (mm) and Clamping Torque effect using the Various combinations of parameters were constructed using factorial design and responses, resulting in a comprehensive factorial analysis. Conspicuous changes in the tensile strength, yield strength, hardness, and power profile were observed for all amalgamations of parameters. Significant parameters of the FSW process have been considered in many optimization studies, however, the effect of the Clamp Pitch (mm) and Clamping Torque (Nm) has been never studied. Three levels of three parameters were used in the experiments: Clamp Pitch, tool rotational speed and Clamping Torque. The full factorial analysis was performed, was applied as an approach for selecting the values of the Significant factors of the parameters. For each result the three key parameters were important with p-values of less than 0.05, suggesting their significance in the phase of FSW. Mathematical models built with high R-sq. and least percentage error were adequate for the investigated responses. The findings were gained by important parameter values factors of 30 mm, 1800 rpm and 70 Nm for the take into consideration parameter range for the Clamp Pitch, rotational speed and Clamping Torque respectively.