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Number of results: 4
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Biomimetic scaffolds based on chitosan in bone regeneration. A review

Anna Kołakowska Agnieszka Gadomska-Gajadhur Paweł Ruśkowski
Chemical and Process Engineering | 2022 | vol. 43 | No 3 | 305-330 | DOI: 10.24425/cpe.2022.142277
Keywords chitosan scaffolds biocompatibility bone regeneration
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Abstract

Chitosan (CS) is a polysaccharide readily used in tissue engineering due to its properties: similarity to the glycosaminoglycans present in the body, biocompatibility, non-toxicity, antibacterial character and owing to the fact that its degradation that may occur under the influence of human enzymes generates non-toxic products. Applications in tissue engineering include using CS to produce artificial scaffolds for bone regeneration that provide an attachment site for cells during regeneration processes. Chitosan can be used to prepare scaffolds exclusively from this polysaccharide, composites or polyelectrolyte complexes. A popular solution for improving the surface properties and, as a result enhancing cellbiomaterial interactions, is to coat the scaffold with layers of chitosan. The article focuses on a polysaccharide of natural origin – chitosan (CS) and its application in scaffolds in tissue engineering. The last part of the review focuses on bone tissue and interactions between cells and chitosan after implantation of a scaffold and how chitosan’s structure affects bone cell adhesion and life processes.
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Authors and Affiliations

Anna Kołakowska
1
ORCID: ORCID
Agnieszka Gadomska-Gajadhur
1
ORCID: ORCID
Paweł Ruśkowski
1
ORCID: ORCID
  1. Faculty of Chemistry, Warsaw University of Technology, Noakowskiego 3, 00-664 Warsaw, Poland

Biocompatibile TiN-based novel nanocrystalline films

R. Ebner J.M. Lackner W. Waldhauser R. Major E. Czarnowska R. Kustosz P. Lacki B. Major
Bulletin of the Polish Academy of Sciences Technical Sciences | 2006 | vol. 54 | No 2 | 167-173
Keywords titanium nitride thin films polyurethane biocompatibility finite element modelling
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Abstract

Titanium nitride (TiN) is regarded as a potential biomaterial for blood-contact applications. TiN thin films were fabricated by pulsed

laser deposition with the Nd:YAG laser on biologically applied polyurethane. Transmission electron microscopy (TEM) study of 250 nm thick films revealed columnar structure. Such films were observed to be brittle, which led to crack formation and secondary nucleation of microcolumn. TEM studies showed a kinetic mechanism of growth (columnar) in films of 250 nm thickness. It was stated that thinner films were much smoother and uniform than the thicker ones, which could be associated with the surface diffusion mechanism to appear. In order to improve the coatings elasticity, the thickness was reduced to 50 nm, which limited the deposition mechanism operation to the early stage. TEM cross-section observation revealed elastic properties of thin films. A biological test showed that TiN surface film produced on polyurethane is characterized by good biocompatibility and decreased surface affinity for cell adhesion. Films of 0.25 and 0.5 1m thick of TiN were selected for theoretical finite element modelling (FEM) using ADINA program. The micro cracks formation predicted in simulation was verified by phenomena observed in microstructure examinations.

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Authors and Affiliations

R. Ebner
J.M. Lackner
W. Waldhauser
R. Major
E. Czarnowska
R. Kustosz
P. Lacki
B. Major

Corrosion Assessment of Nickel – Base – Dental Alloys in Ringer Biological Solution Studied by Electrochemical Techniques

L. Benea L. Dragus D. Mocanu
Archives of Metallurgy and Materials | 2022 | vol. 67 | No 2 | 529-533 | DOI: 10.24425/amm.2022.137786
Keywords Corrosion Biocompatibility Dental alloys Ringer fluid Dental bridge electrochemical methods
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Abstract

The aim of this paper was to study the corrosion behavior of Nickel – Base – Dental Alloys in Ringer biological fluid. The Nickel base alloys are widely used for medical purposes, especially for prosthetic works in the field of dentistry. The applied electrochemical methods used for corrosion investigations are Open Circuit Potential, Linear Polarization during time of immersion in order to calculate the polarization resistance and corrosion rate. Potentiodynamic Polarization diagrams was performed to appreciate the passive domain. Ni-Cr Ugirex alloy show a better corrosion resistance in Ringer solution which will be reflected in a longer life of the dental structures made with this alloy as compared to the Ni-Cr Ducinox alloy, which will result in dental structures with a shorter lifespan.
The electrochemical studies has shown that the alloy have a corrosion behavior similar to a passivating alloy, displaying an extensive passivity area due to formation of an oxide film.
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Authors and Affiliations

L. Benea
1
ORCID: ORCID
L. Dragus
1 2
D. Mocanu
1
  1. Dunarea de Jos University of Galati, Competences Centre: Interfaces-Tribocorrosion and Electrochemical Systems (CC-ITES), 47 Domneasca Street, RO-800008 Galati, Romania
  2. Dunarea de Jos University of Galati, Faculty of Medicine and Pharmacy, 35 Alexandru. I. Cuza Street., RO-800010, Galati, Romania

Structural and Physical Characterization of New Ti-Based Alloys

I. Baltatu A.V. Sandu M.S. Baltatu M. Benchea D.C. Achitei F. Ciolacu M.C. Perju P. Vizureanu L. Benea
Archives of Metallurgy and Materials | 2022 | vol. 67 | No 1 | 255-259 | DOI: 10.24425/amm.2022.137499
Keywords new biomaterials titanium alloys biocompatible elements β phase
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Abstract

Production of Ti-based alloys with non-toxic elements give the possibility to control the market of medical applications, using alloys with appropriate properties for human body, contributing to improving the health of the population. Determination of parameters of atomic and magnetic structure of functional biomaterials demonstrating interesting physical phenomena and being promising for medical applications in a wide range of thermodynamic parameters; exploration of the role of cluster aggregation in the formation of physical properties. Paper is about the obtaining of the new titanium system alloys, the determining their characteristics and structure, and obtaining information concerning phase transitions and some mechanical properties. Ti15Mo7ZrxTa (5 wt.%, 10 wt.% and 15 wt.%) alloys developed shows a predominant β phase highlighted by optical microstructure and XRD patterns. A very low young modulus of alloys was obtained (43-51 GPa) which recommends them as very good alloys for orthopedic applications.
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Authors and Affiliations

I. Baltatu
1
ORCID: ORCID
A.V. Sandu
1 2 3
ORCID: ORCID
M.S. Baltatu
1 2
ORCID: ORCID
M. Benchea
4
ORCID: ORCID
D.C. Achitei
1 2
ORCID: ORCID
F. Ciolacu
5
ORCID: ORCID
M.C. Perju
1 2
ORCID: ORCID
P. Vizureanu
1 2
ORCID: ORCID
L. Benea
6
ORCID: ORCID
  1. “Gheorghe Asachi” Technical University of Iasi, Faculty of Materials Science and Engineering, 41 “D. Mangeron” Street, 700050, Iasi, Romania
  2. University Malaysia Perlis, Centre of Excellence Geopolymer & Green Technology School of Materials Engineering, Kompleks Pengajian Jejawi 2,02600 Arau, Perlis
  3. Romanian Inventors Forum, Str. Sf. P. Movila 3, L11, 700089, Iasi, Romania
  4. “Gheorghe Asachi” Technical University of Iasi, Faculty of Mechanical Engineering, 61-63 “D. Mangeron” Street, 700050, Iasi, Romania
  5. “Gheorghe Asachi” Technical University of Iasi, Department of Natural and Synthetic Polymers, 73 Blvd. D. Mangeron, Iasi, 700050, Romania
  6. Dunărea de Jos University of Galati, Faculty of Engineering, 47 Domneasca St., 800008, Galati, Romania

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