The new challenges for Polish theology in the beginning of the 21st c. in the context of possession and exorcism include a theological reflection on possession and exorcism in the Bible, in patristic texts as well as in medieval and modern theological literature. Another issue is an elaboration of a new theological anthropology, which should acknowledge the achievements of human sciences like psychology and psychiatry. The existence of the psychic sphere in the human being is to be distinguished while the human spiritual sphere is to be convincingly justified. More precise criteria will be needed in order to distinguish psychic problems from those of a spiritual nature, including possession.