The present work deals with agitation of non-Newtonian fluids in a stirred vessel by Scaba impellers. A commercial CFD package (CFX 12.0) was used to solve the 3D hydrodynamics and to characterise at every point flow patterns especially in the region swept by the impeller. A shear thinning fluid with yield stress was modelled. The influence of agitator speed, impeller location and blade size on the fluid flow and power consumption was investigated. The results obtained are compared with available experimental data and a good agreement is observed. It was found that an increase in blade size is beneficial to enlargement of the well stirred region, but that results in an increased power consumption. A short distance between the impeller and the tank walls limits the flow around the agitator and yields higher power consumption. Thus, the precise middle of the tank is the most appropriate position for this kind of impeller.