Regional differentiation of economic growth in Poland between 1995 and 2015. The paper explores the regional differentiation of economic growth in Poland between 1995 and 2015 in terms of GDP per capita. The historically lagging-behind regions of eastern Poland has shown relatively high dynamics and reduced the gap vis-à-vis Western European regions. At the same time, they have not been catching up with the fastest growing metropolitan areas, which leads to increased inter-regional disparities in the country. The lowest rate of growth is characteristic of northern regions and western borderland, which is related to their social and cultural features, including poor human capital, and limited internal market. There is moderate correlation between regional economic growth and the quality of life. The least favourable situation in both respects is found in the German borderland.