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The importance of the quality of information and the methods of its distribution in the process of promoting a healthy lifestyle

Artur Fałek Franciszek Burdan
Folia Medica Cracoviensia | 2022 | Vol. 62 | No 1 | 89-101 | DOI: 10.24425/fmc.2022.141693
Keywords communication pictogram interpersonal relationship health promotion
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Abstract

Each piece of information is distributed in the form of a message. Its character takes various forms, it can be expressed by words or in images. It is the visual form which is the most effective tool of influence. Graphic signs are often used to convey or exchange thoughts. The signs have an informative function but they are also meant to force a specific behavior. Such a change in expectations and beliefs of a specific regulator is called the social impact. The intensity of interpersonal relationships is deliberately stimulated through an appropriate form of communication. The more expressive and emotional is its character, the greater the benefits for the quality of communication in the process of promoting healthy behaviors.
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Authors and Affiliations

Artur Fałek
1
Franciszek Burdan
2
  1. Independent Public Healthcare, Puławy, Poland
  2. St. John’s Cancer Center; Human Anatomy Department, Medical University of Lublin, Lublin, Poland

Malakoplakia of the urinary system

Katarzyna Cięszczyk Michał Puderecki Lech Wronecki Franciszek Burdan Justyna Szumiło
Folia Medica Cracoviensia | 2019 | vol. 59 | No 2 | 67-74 | DOI: 10.24425/fmc.2019.128455
Keywords malakoplakia von Hansemann cells Michaelis-Gutmann bodies
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Abstract

Malakoplakia is regarded as a chronic granulomatous infl ammatory disease with a good prognosis. It usually aff ects the urinary system, especially the urinary bladder. Bacterial infections, including E. coli are thought to be the main factor in pathogenesis. It frequently coexists with chronic diseases and immunosuppression state. Histopathological examination of aff ected tissue samples is thought to be the best diagnostic method. Th e basic microscopic feature is mixed infl ammatory infi ltration containing foamy histiocytes known as von Hansemann cells, frequently with basophilic inclusions known as Michaelis-Gutmann bodies. Symptoms and the clinical course of malakoplakia depend on location and the extent of the lesions. Th e lesion is treated successfully with antibiotic therapy and surgical excision.

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Authors and Affiliations

Katarzyna Cięszczyk
Michał Puderecki
Lech Wronecki
Franciszek Burdan
Justyna Szumiło

Melanoma of the gallbladder

Paweł Bojar Franciszek Burdan Lech Wronecki Justyna Szumiło
Folia Medica Cracoviensia | 2023 | Vol. 63 | No 2 | 77-92 | DOI: 10.24425/fmc.2023.145915
Keywords melanoma gallbladder epidemiology imaging morphology outcome
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Abstract

Melanoma is a highly malignant neoplasm with the most typical primary locations in the skin and eyeball and rarely reported in the other organs, including the gallbladder. More commonly metastases of melanoma of various primary sites to the gallbladder are observed. However, generally melanoma of the gallbladder is a rare entity with only 217 cases reported in the literature up to date. The paper summarizes knowledge on epidemiology, symptoms, laboratory and imaging findings, morphology, treatment options, and outcome of patients with both primary and metastatic melanoma to the gallbladder.
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Authors and Affiliations

Paweł Bojar
1 2
Franciszek Burdan
3 4
Lech Wronecki
1
Justyna Szumiło
1
  1. Department of Clinical Pathomorphology, Medical University of Lublin, Lublin, Poland
  2. Department of Pathomorphology, Beskid Oncology Centre — John Paul II Memorial City Hospital in Bielsko-Biala, Bielsko-Biała, Poland
  3. Department of Human Anatomy, Medical University of Lublin, Lublin, Poland
  4. epartment of Radiology, St Johns’ Cancer Center, Lublin, Poland

Detecting undetectable — epidemiology, etiology, and diagnosis of carcinoma of unknown primary — systematic review

Justyna Ostojewska Iga Wieczorek Olaf Pachciński Wojciech Zdziennicki Franciszek Burdan
Folia Medica Cracoviensia | 2023 | Vol. 63 | No 1 | 19-37 | DOI: 10.24425/fmc.2023.145427
Keywords cancer carcinoma of unknown primary metastases diagnostics
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Abstract

Carcinoma of unknown primary (CUP) is a heterogeneous group of oncological diseases in which it is impossible to determine the primary tumor. The incidence is 3–5% of oncologic patients, but the survival time varies from 6 weeks to 5 months.
The diagnostics should begin with a clinical evaluation and basic laboratory tests. For CUP placed in head and neck the positron emission tomography — computed tomography is recommended; pancreatic or lung neoplasms are diagnosed with the computed tomography as well. Recently, the magnetic resonance, especially whole-body diffusion-weighted imaging has been introduced to the imaging panel. The lesion obtained during surgically removed metastases or biopsy material should be histopathological and mole-cularly examined to define the type of tumor. The basic immunoexpression panel should include cyto-keratin-5/6, -7 and -20, EMA, synaptophysin, chromogranin, vimentin and GATA3 and molecular ex-pression of ERBB2, PIK3CA, NF1, NF2, BRAF, IDH1, PTEN, FGFR2, EGFR, MET and CDK6. During the accurate diagnostics enable to classify malignancy of undefined primary origin as provisional CUP or finally confirmed CUP in which the primary place of tumor remains undetectable. The detailed diag-nostics should be performed in highly specified centers to establish an accurate diagnosis and to initiate personalized treatment. Majority of patients are diagnosed with adenocarcinoma (70%), undifferentiated carcinoma (20%), squamous cell or transitional cell/uroepithelial carcinoma (5–10%), neuroendocrine tumor (5%) and with minor incidence other histological types, including melanoma.
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Authors and Affiliations

Justyna Ostojewska
1
Iga Wieczorek
1
Olaf Pachciński
1
Wojciech Zdziennicki
1
Franciszek Burdan
1 2
  1. Chair and Department of Human Anatomy, Medical University of Lublin, Lublin, Poland
  2. Diagnostics Imaging Department, St. John Cancer Center, Lublin, Poland

Pro-health measures as a creator of new behavior norms and attitudes

Paulina Fałek Tomasz Adamczyk Artur Fałek Franciszek Burdan
Folia Medica Cracoviensia | 2022 | Vol. 62 | No 4 | 35-44 | DOI: 10.24425/fmc.2022.144081
Keywords health healthy lifestyle physical activity health behavior health promotion
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Abstract

The monograph analyzes health behaviors and main factors on the basis of which it is possible to transform a lifestyle generally focused on the well-being of an individual and society. According to WHO, health is a state of complete physical, mental and social well-being, and not only the absence of a disease. The definition clearly explains its multidimensional and multithreaded character dependent subjectively on every individual and on social and cultural conditions. Health in its general meaning becomes a sub-jective human feeling. Each individual plays an important role in the process of providing it. Good health condition can be achieved by proper nutrition, regular doctor’s check-up visits and active way of life. Health behaviors are still a key element of the daily activity of everyone. Despite the fact that full knowl-edge of the concept of “healthy lifestyle” prevails, still many people avoid categorical statements. In response to questions about lifestyle, a significant number of respondents often indicate an intention or willingness to change, or to partially comply with the requirements, which results from weakness and lack of determination in action. Knowledge supported by the offer of attractive models that promote the right patterns of behavior can have a positive impact on the global health of the society.
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Authors and Affiliations

Paulina Fałek
1
Tomasz Adamczyk
2
Artur Fałek
1
Franciszek Burdan
3 4
  1. Independent Public Healthcare, Puławy, Poland
  2. The Institute of Sociological Sciences, Faculty of Social Sciences, The John Paul II Catholic University of Lublin, Lublin, Poland
  3. Human Anatomy Department, Medical University of Lublin, Lublin, Poland
  4. Department of Radiology, St. John Cancer Center, Lublin, Poland

Selected morphological and mechanical features of the femur of pregnant rats after exposure to caffeine applied at various temperatures. Caffeine in the nutrition of pregnant rats

Monika Cendrowska-Pinkosz Wojciech Dworzański Magdalena Krauze Paulius Matuseviĉius Katarzyna Ognik Franciszek Burdan
Folia Medica Cracoviensia | 2021 | Vol. 61 | No 1 | 95-108 | DOI: 10.24425/fmc.2021.137216
Keywords 1,3,7-methylxanthine bone metabolism bone rigility
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Abstract

It was assumed that the temperature at which caffeine is consumed may cause changes in the mechanical and morphological properties of bones and affect the bone metabolism of pregnant female. The aim of the study was to assess the effect of caffeine used at different temperatures on selected morphological and mechanical properties of the femur as well as biochemical indicators of bone formation in female rats in pregnancy. It was use test solution at the temperature 10, 25 and 45ºC from 8 to 21 day during pregnancy, once a day. It was found that the temperature of administrated caffeine may have an effect on changing the morphometric properties and on the bone metabolism of pregnant female rats. The application of caffeine solution, was administrated at 10ºC caused the most constrained growth of the femur and weakened resistance to load, and caused increased susceptibility to cracks. Analysis of bone metabolism indicators showed that caffeine administered in the form of a solution at 10ºC and 25ºC caused the most negativity effects for bone formation and bone turnover indicators. The administration of caffeine at 10ºC causes the largest negative changes in bone morphological and strength indicators and hasn’t a beneficial effect on the bone metabolism of pregnant female rats.
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Authors and Affiliations

Monika Cendrowska-Pinkosz
1
Wojciech Dworzański
1
Magdalena Krauze
2
Paulius Matuseviĉius
3
Katarzyna Ognik
2
Franciszek Burdan
1
  1. Department of Human Anatomy, Medical University in Lublin, Lublin, Poland
  2. Department of Biochemistry and Toxicology, University of Life Sciences in Lublin, Lublin, Poland
  3. Department of Animal Nutrition, Lithuanian University of Health, Kaunas, Lithuania

Information impact on synaptic arousal and formation of permanent memory trace

Paulina Fałek Artur Fałek Monika Kager Richard Kager Piotr Walkowicz Marcin Kubiak Elżbieta Starosławska Franciszek Burdan
Folia Medica Cracoviensia | 2021 | Vol. 61 | No 3 | 33-42 | DOI: 10.24425/fmc.2021.138949
Keywords memory memory trace consolidation brain plasticity engram emotions
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Abstract

Memory trace is an effect of temporary arousal (perception, experience, action) that causes a specific change in the nervous system. Memory allows to record and recall various information, thus enabling to learn new things. It is an extremely active and dynamic process. The influence of emotions on memory is obvious, largely determined by the close cooperation of the amygdala (responsible for emo-tions) and the hippocampus (memory processes).
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Authors and Affiliations

Paulina Fałek
1
Artur Fałek
1
Monika Kager
2
Richard Kager
3
Piotr Walkowicz
2
Marcin Kubiak
2
Elżbieta Starosławska
2
Franciszek Burdan
2 4
  1. Independent Public Healthcare, Puławy, Poland
  2. St. John’s Cancer Center, Lublin, Poland
  3. Public Independent Clinical Hospital Number 4, Lublin, Poland
  4. Human Anatomy Department, Medical University of Lublin, Lublin, Poland

Coexistence of isolated internal iliac artery aneurysm with uterine cervical carcinoma

Franciszek Burdan Krzysztof Czarnocki Agnieszka Mocarska Maciej Burdan Iwonna Żelazowska-Cieślińska Elżbieta Starosławska
Folia Medica Cracoviensia | 2021 | Vol. 61 | No 1 | 49-56 | DOI: 10.24425/fmc.2021.137212
Keywords internal iliac artery aneurysms cervical carcinoma aneurysm epidemiology aneurysm risk factors aneurysm symptoms
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Abstract

Isolated internal iliac artery aneurysms are rarely described in the available literature. The paper presents a case of a 70-year-old female with idiopathic thrombocytopenia, squamous cell cervical carci-noma, and saccular aneurysm of the left internal iliac artery, detected in magnetic resonance. The review of aneurysm of the common, external and internal iliac arteries is added.
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Authors and Affiliations

Franciszek Burdan
1 2
Krzysztof Czarnocki
1
ORCID: ORCID
Agnieszka Mocarska
1
Maciej Burdan
2
Iwonna Żelazowska-Cieślińska
1
Elżbieta Starosławska
1
  1. St. John’s Cancer Centre, Lublin, Poland
  2. Human Anatomy Department, Medical University of Lublin, Lublin, Poland

Tenosynovial giant cell tumor

Monika Kager Richard Kager Paulina Fałek Artur Fałek Grzegorz Szczypiór Joanna Niemunis-Sawicka Ludomira Rzepecka-Wejs Elżbieta Starosławska Franciszek Burdan
Folia Medica Cracoviensia | 2022 | Vol. 62 | No 2 | 93-107 | DOI: 10.24425/fmc.2022.141702
Keywords pigmented villonodular synovitis PVNS tenosynovial giant cell tumor epidemiology diagnosis treatment
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Abstract

Tenosynovial Giant Cell Tumor (TGCT) is a group of typically benign lesions arising from the synovium of joints, bursae and tendon sheaths. Depending on their growth pattern and clinical course, they are divided into localized and diffuse types. It is predominantly caused by a mutation in the stromal cells of the synovial membrane leading to overexpression of the colony stimulating factor 1 that recruits CSF1R-expressing cells of the mononuclear phagocyte lineage into the tumor mass. The lesions contain mainly histiocyte-like and synovial cells accompanied by varying numbers of multinucleated giant cells, mononuclear cells, foam cells, inflammatory cells and hemosiderin deposits. The gold standard for detect-ing and monitoring the disease is MRI, where the characteristic hemosiderin accumulation can be best appreciated, but it is a histological examination that is most conclusive. The main treatment is surgical resection of all pathological tissue, but radio- and chemotherapy are also viable options for certain groups of patients.
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Authors and Affiliations

Monika Kager
1
Richard Kager
2
Paulina Fałek
3
Artur Fałek
3
Grzegorz Szczypiór
4
Joanna Niemunis-Sawicka
4 5
Ludomira Rzepecka-Wejs
6
Elżbieta Starosławska
1
Franciszek Burdan
1 7
  1. Radiology Department, St Johns’ Cancer Center, Lublin, Poland
  2. Public Independent Clinical Hospital Number 4, Lublin, Poland
  3. Independent Public Healthcare, Puławy, Poland
  4. MRI Unit of Maritime Medical Center, Gdańsk, Poland
  5. 2nd Radiology Department, Medical University of Gdańsk, Gdańsk, Poland
  6. Goris-Med, Gdańsk, Poland
  7. Human Anatomy Department, Medical University of Lublin, Lublin, Poland

Pigmented villonodular synovitis

Artur Fałek Joanna Niemunis-Sawicka Katarzyna Wrona Grzegorz Szczypiór Ludomira Rzepecka-Wejs Katarzyna Cięszczyk Maciej Burdan Michał Puderecki Paulina Burzec Barbara Marzec-Kotarska Justyna Szumiło Franciszek Burdan
Folia Medica Cracoviensia | 2018 | vol. 58 | No 4 | 93-104 | DOI: 10.24425/fmc.2018.125707
Keywords pigmented villonodular synovitis PVNS tenosynovial giant cell tumor epidemiology diagnosis
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Abstract

Pigmented villonodular synovitis (PVNS) is a benign disease that rarely undergoes malignant transformation. Th ere are two types of disease: localized (nodular tenosynovitis) and diff used (pigmented villonodular synovitis/tenosynovitis) with intra- or extra-articular locations. Th e second one is limited to synovium of the burse (PVNB) or tendon sheath (PVNTS). Th e intraarticular lesions are usually located in the knee, hip, ankle and elbow joints. Histologically, PVNS is a tenosynovial giant cell tumor, characterized by proliferation of two types of mononuclear cells — predominantly small, histiocyte-like cells and larger cells with dense cytoplasm, reniform or lobulated nucleus, with accompanying multinucleated giant cells and macrophages overloaded with hemosiderin that give typical image on MRI — currently selected as a gold standard for its diagnosis. Th e classic X-ray and CT are non-specifi c but similar to ultrasound should be used to evaluate disease progression and treatment response if radiotherapeutic and pharmacological methods were selected for treatment. An open arthroscopic surgery could also be applied in selected cases.

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Authors and Affiliations

Artur Fałek
Joanna Niemunis-Sawicka
Katarzyna Wrona
Grzegorz Szczypiór
Ludomira Rzepecka-Wejs
Katarzyna Cięszczyk
Maciej Burdan
Michał Puderecki
Paulina Burzec
Barbara Marzec-Kotarska
Justyna Szumiło
Franciszek Burdan

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