The aim of the study was to determine the influence of selected nanoparticles, namely diesel exhaust particles, Arizona test dust, silver and gold on the rheology of human blood. The rheological properties of human blood were determined with the use of a modular rheometer, at two various temperatures, namely 36.6◦C and 40◦C. Experimental results were used to calculate the constants in blood constitutive equations. The considered models were power-law, Casson and Cross ones. The obtained results demonstrate that the presence of different nanoparticles in the blood may have different effect on its apparent viscosity depending on the type of particles and shear rate.