Antibiotics are used for postsurgical wound healing purposes but unfortunately, resistance against them demands some alternatives for quick recovery. Sepsis of wounds is a challenge for medical as well as veterinary professionals. Nanoparticles have significant advantages in wound treatment and drug resistance reversal. This study was conducted to appreciate emerging alternates of antibiotics like zinc oxide nanoparticles and plant extracts in topical application. Zinc oxide is considered a good wound healer and its nanoparticles are easy to access. So, the efficacies of zinc oxide nanoparticles and sweet flag plant extract ointments were tested to compare modern and traditional therapeutics as sweet flag is considered a pure medicinal plant. Rabbits were selected for this study due to the healing properties of their skin. Wounds were inflicted on the thoracolumbar region and treated for 29 days post-surgically daily with normal saline and the ointment of zinc oxide nanoparticles and sweet flag extract ointment, prepared in a hydrophilic solvent. Wound shrinkage was observed daily and histopathological analysis was made and results were compared. Zinc oxide nanoparticles ointment showed the most satisfactory results for every parameter included in the study. No side effects of its topical application were observed. Healing was normal without any complications. The preparations of zinc oxide nanoparticles may help in the era of antibiotic resistance as topical drugs in the future.

A novel phase shift full bridge (PSFB) converter with voltage-doubler and decoupling integrated magnetics in photovoltaic (PV) systems is proposed. Considering the demand that the output voltage is higher than the input voltage in PV systems, the voltage-doubler is added to achieve higher voltage gain compared with the traditional PSFB. In order to avoid current oscillation caused by the voltage-doubler and obtain the wide zero voltage switching (ZVS) ranges, an external inductor is imposed on the circuit. Especially, to obtain much higher power density, the external inductor and transformer are integrated into one magnetic core. The operation and voltage gain of proposed converter are analyzed. Also, in order to reveal the effects the integrated magnetics gives to the converter, the decoupling condition and the expression of leakage inductor of integrated magnetics are obtained in detail. Finally a 100 W prototype converter is made and the experimental results are given to verify the analysis.