Details

Title

Impact of bioreactor scale on lovastatin biosynthesis by Aspergillus terreus ATCC 20542 in a batch culture

Journal title

Chemical and Process Engineering

Yearbook

2012

Numer

No 1 March

Authors

Keywords

lovastatin ; Aspergillus terreus ATCC 20542 ; shake flask ; stirred tank bioreactor ; batch process

Divisions of PAS

Nauki Techniczne

Coverage

71-84

Publisher

Polish Academy of Sciences Committee of Chemical and Process Engineering

Date

2012

Type

Artykuły / Articles

Identifier

ISSN 0208-6425

References

Bizukojć M. (2007a), A macrokinetic modelling of the biosynthesis of lovastatin by, Aspergillus terreus. J. Biotechnol, 130, 422, doi.org/10.1016/j.biotec.2007.05.007 ; Bizukojć M. (2007b), Simultaneous biosynthesis of (+)-geodin by a lovastatin-producing fungus, Aspergillus terreus. J. Biotechnol, 132, 453, doi.org/10.1016/j.jbiotec.2006.06.017 ; Bizukojć M. (2008), Biosynthesis of lovastatin and (+)-geodin by <i>Aspergillus terreus</i> in batch and fed-batch culture in the stirred tank bioreactor, Biochem. Eng, 42, 198, doi.org/10.1016/j.bej.2008.06.022 ; Bizukojć M. (2011), Lovastatin and (+)-geodin formation by <i>Aspergillus terreus</i> ATCC 20542 in a batch culture with the simultaneous use of lactose and glycerol as carbon sources, Eng. Life Sci, 11, 272, doi.org/10.1002/elsc.201000179 ; J. Casas Lopez (2003), Production of lovastatin by <i>Aspergillus terreus:</i> effects of C:N ratio and the principal nutrients on growth and metabolite production, Enzyme Microb. Technol, 33, 270, doi.org/10.1016/S0141-0229(03)00130-3 ; J. Casas Lopez (2004), Fermentation optimization for the production of lovastatin by <i>Aspergillus terreus</i>; use of response surface methodology, J. Chem. Technol. Biotechnol, 79, 1119, doi.org/10.1002/jctb.1100 ; J. Casas Lopez (2005), Pellet morphology, culture rheology and lovastatin production in cultures of, Aspergillus terreus. J. Biotechnol, 116, 61, doi.org/10.1016/j.jbiotec.2004.10.005 ; Hajjaj H. (2001), Lovastatin biosynthesis by <i>Aspergillus terreus</i> in a chemically defined medium, Appl. Environ. Microbiol, 67, 2596, doi.org/10.1128/AEM.67.6.2596-2602.2001 ; Kennedy J. (1999), Modulation of polyketide synthase activity by accessory proteins during lovastatin biosynthesis, Science, 284, 1368, doi.org/10.1126/science.284.5418.1368 ; Kumar M. (2000), Repeated fed-batch process for improving lovastatin production, Proc. Biochem, 36, 363, doi.org/10.1016/S0032-9592(00)00222-3 ; Lai L-S. (2002), Medium optimization for lovastatin production by Aspergillus terreus in submerged cultures, J. Chin. Inst. Chem. Engrs, 33, 517. ; L-S Lai (2005), The influence of culturing environments on lovastatin production by <i>Aspergillus terreus</i> in submerged cultures, Enz. Microb. Technol, 36, 737, doi.org/10.1016/j.enzmictec.2004.12.021 ; Manzoni M. (1998), Production of statinsby filamenous fungi, Biotechnol. Lett, 21, 253, doi.org/10.1023/A:1005495714248 ; E. Rodriguez Porcel (2006), <i>Aspergillus terreus</i> broth rheology, oxygen transfer, and lovastatin production in a gas-agitated slurry reactor, Ind. Eng. Chem. Res, 45, 4837, doi.org/10.1021/ie0600801

DOI

10.2478/v10176-012-0007-0

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