TY - JOUR N2 - A clinical trial was performed to evaluate the therapeutic efficacy of osaterone acetate (OSA) in the treatment of benign prostatic hyperplasia (BPH) in dogs. Osaterone acetate (Ypozane, Virbac) was administered orally at a dose of 0.25 mg/kg body weight once a day for seven days to 23 dogs with BPH. During the 28-day trial, the dogs were monitored five times for their clinical signs and prostate volume. The OSA treatment promoted rapid reduction of clinical scores to 73.2% on day 7 and to 5.9% on day 28 (p<0.05). Osaterone acetate induced the complete clinical remission in approximately 83.0% of the dogs on day 28. The prostate volume regressed to 64.3% of the pretreatment volume after two weeks of the treatment (p<0.05) and to 54.7% at the end of the trial (p<0.05). In conclusion, OSA quickly reduced clinical signs and volume of the prostate glands in dogs with BPH. L1 - http://www.czasopisma.pan.pl/Content/109593/PDF/18.pdf L2 - http://www.czasopisma.pan.pl/Content/109593 PY - 2018 IS - No 4 EP - 797–802 DO - 10.24425/pjvs.2018.125601 KW - dogs KW - benign prostatic hyperplasia KW - osaterone acetate KW - prostate volume A1 - Socha, P. A1 - Zduńczyk, S. A1 - Tobolski, D. A1 - Janowski, T. PB - Polish Academy of Sciences Committee of Veterinary Sciences PB - University of Warmia and Mazury in Olsztyn VL - vol. 21 DA - 2018.12.20 T1 - The effects of osaterone acetate on clinical signs and prostate volume in dogs with benign prostatic hyperplasia SP - 797–802 UR - http://www.czasopisma.pan.pl/dlibra/publication/edition/109593 T2 - Polish Journal of Veterinary Sciences ER -