@ARTICLE{Skwarcz_S._The_2019, author={Skwarcz, S. and Bryzek, I. and Gregosiewicz, A. and Warda, E. and Gawęda, K. and Tarczyńska, M. and Skwarcz, J. and Nadulski, R. and Starek, A. and Sanford, J.}, volume={vol.22}, number={No 2}, journal={Polish Journal of Veterinary Sciences}, pages={243–250}, howpublished={online}, year={2019}, publisher={Polish Academy of Sciences Committee of Veterinary Sciences}, publisher={University of Warmia and Mazury in Olsztyn}, abstract={The purpose of the study was to assess the effect of autologous activated platelet-rich plasma on healing of a bone substitute - tricalcium phosphate hydroxyapatite in experimental long bone defects using an animal model. The experiment involved an animal model of femoral defect. 24 Termond white rabbits were used in the study. We evaluated the effect of autologous platelet-rich plasma on tricalcium phos- phate using classical radiology, micro-CT studies, strength tests and histological evaluation. Radiological and histological assessment did not show a beneficial effect of PRP together with a bone substitute in comparison to filling the defects only with bone replacement material. The only benefit of adding platelet-rich plasma to a bone substitute was shown in microCT imaging. Autologous, activated platelet-rich plasma combined with hydroxyapatite tricalcium phos- phate has a positive effect on the remodeling of the newly formed bone tissue, increasing its density.}, type={Article}, title={The effect of activated platelet-rich plasma (PRP) on tricalcium hydroxyapatite phosphate healing in experimental, partial defects of long bone shafts in animal models}, URL={http://www.czasopisma.pan.pl/Content/110892/PDF/07.pdf}, doi={10.24425/pjvs.2019.127092}, keywords={platelet-rich plasma, hydroxyapatite tricalcium phosphate, bone regeneration, bone defects, rabbit model}, }